NFL Picks: Thursday Night Football

NFL Picks: Thursday Night Football

Another week of NFL games is here, and that means it's time to cash some NFL bets! This week's Thursday Night Football clashes feature some of the NFL most storied rivalries, and we've got the inside scoop on where to place your bets.

Our expert team at BetQL has dissected the stats, analyzed player form and scrutinized past performances, all thanks to BetQL, to bring you the most informed NFL picks for this prime-time battle.

Our NFL picks are the result of a thorough process that combines data-driven analysis with a deep understanding of the game. Whether you're a seasoned bettor or just starting out, our NFL picks are tailored to give you the upper hand.

So, join us as we break down the key players, strategies and potential game-changers in this electrifying contest. Below, you’ll see a betting breakdown with expert NFL picks from the BetQL Editorial Team, including sleeper picks and epic sportsbook promotions to cash in on!

As always, BetQL is your one-stop destination for live NFL betting odds, sharp picks, public bets, line movement data, exclusive articles and much more to help you cash more bets. BetQL subscribers can see all of this week's best bets with game projections, player props, betting trends and more!

MORE: TNF PLAYER PROPS

TNF: New England at Chicago

NFL Game Prediction: New England Patriots vs. Chicago Bears

We have trending betting tips for the upcoming game between the Chicago Bears and New England Patriots on Thursday, October 22, 2026. Set to take place at Soldier Field, this matchup promises to be exciting as both teams look to solidify their standings in the NFL.

Chicago Bears Overview

The Chicago Bears, under head coach Ben Johnson, have had an energetic start to their season. Currently positioned at 12th in the league standings with 0 points, they have a record of 4 wins and 2 losses so far this season. Fans will hope the Bears can leverage their home advantage to score an important victory.

Last 5 Games:

• Won against Atlanta Falcons: 31-23
• Lost to Green Bay Packers: 7-31
• Won against New York Jets: 23-12
• Won against Philadelphia Eagles: 27-7
• Lost to Minnesota Vikings: 3-9

The Bears have showcased their ability to compete fiercely, and their recent performances suggest they're gaining momentum. Key player statistics are not currently available, but if you'd like more information on individual performances, let us know!

New England Patriots Overview

The New England Patriots, coached by Mike Vrabel, are currently sitting at 7th in the league standings, with a similar record of 4 wins and 2 losses. They have a total of 136 points scored against them, showcasing their resilience on the field.

Last 5 Games:

• Won against New York Jets: 26-19
• Won against Las Vegas Raiders: 45-17
• Won against Buffalo Bills: 29-26
• Lost to Jacksonville Jaguars: 6-35
• Won against Pittsburgh Steelers: 20-3

The Patriots have displayed consistency this season, reflecting a balanced attack and strong defensive strategy. Individual player statistics were not accessible, but we can provide more on specific player performances if needed.

Head-to-Head Statistics

The Chicago Bears and New England Patriots have faced each other multiple times in previous seasons. Notable recent results have seen the Bears put up solid performances, although specific scores from the prior engagements are not available.

Predictions for the Game

1. Moneyline Prediction: Our NFL prediction is favoring a home win for the Chicago Bears with odds set at -167 through Fanatics Sportsbook.
2. Best NFL Point Spread: The best NFL point spread is favoring the away team, the New England Patriots, with a line at +3.5 points and odds of -125 on Fanatics Sportsbook.
3. Points Total Betting Market: For the total points scored, the line is set at over 49.5 points at odds of -125 on Fanatics Sportsbook.

In summary, this game brings together two teams in pursuit of further establishing their success this NFL season. The Chicago Bears, playing at home, will be eager to build on their recent win against the Falcons, while the New England Patriots aim to continue their strong performance. With intriguing predictions and betting lines, fans are in for a thrilling showdown!

Our top NFL Player Props for Thursday

Drake Maye UNDER 249.5 Passing Yards at -113 on DraftKings Sportsbook

D'Andre Swift UNDER 14.5 Rushes at -109 on DraftKings Sportsbook

AJ Brown UNDER 68.5 Receiving Yards at -112 on DraftKings Sportsbook

For all our top NFL player Props check out our Player prop page

Best Sportsbook Promotions

Check out our plays for today's best sportsbook promotions, including odds boosts and more!

2026 Thursday Night Football Schedule

The 2026 NFL schedule is out which means that we have the complete Thursday Night Football schedule. Let’s take a look at the full exciting schedule below:

How To Bet Thursday Night Football

Research the teams: Before placing any Thursday Night Football bets, it's important to gather information about the teams playing. Consider their recent performance, key players, injuries, head-to-head records, and any other relevant factors that may impact the game.

Understand the odds: Familiarize yourself with how NFL betting odds work. Odds indicate the probability of a specific outcome, and they also determine the potential payout. Learn about different types of bets, such as point spreads, moneylines, and over/unders, and consider which type of bet aligns with your betting strategy.

Set a budget: It's crucial to establish a budget for your Thursday Night Football betting activities and stick to it. Only wager what you can afford to lose, and avoid chasing losses by increasing your bets. Responsible bankroll management is key to maintaining a sustainable and enjoyable betting experience.

Shop for the best odds: Different sportsbooks may offer slightly different Thursday Night Football odds for the same game. Take the time to compare odds from multiple bookmakers to ensure you're getting the best value for your bets. Even small differences in odds can significantly impact your overall profitability in the long run.

Consider additional factors: While statistics and trends are important, also consider other factors that may influence the outcome of a Thursday Night Football game. These factors could include weather conditions, home-field advantage, coaching strategies, and team motivation.

Practice self-control: Emotions can often cloud judgment, leading to impulsive or irrational betting decisions. Try to approach sports betting with a calm and logical mindset. Avoid betting on your favorite Thursday Night Football team solely based on loyalty, as it can bias your judgment.

Remember, Thursday Night Football betting involves an element of risk, and there are no guaranteed outcomes. It's essential to gamble responsibly, be mindful of your betting habits, and enjoy the game within your means.

Be sure to consult BetQL’s NFL Model before placing any Thursday Night Football bets. Also see live public betting, sharp betting and line movement data, player prop projections, trending bets and more!

Thursday Night Football Betting Strategy

When it comes to betting on Thursday night NFL games, here are some strategies you can consider:

Research the teams: Analyze the teams' recent performance, including their records, statistics, and key player injuries. Look at their offensive and defensive capabilities, as well as their past performance in prime-time games.

Consider short weeks: Thursday night games usually occur after a shorter week of preparation, which can impact team performance. Take into account how teams have historically fared in these situations, as some may struggle to perform at their usual level due to less rest and recovery time.

Home-field advantage: Assess the impact of home-field advantage on the teams playing. Some teams tend to perform better at home, so consider this factor when making your predictions.

Weather conditions: Keep an eye on the weather forecast for the game. Extreme weather conditions, such as heavy rain or strong winds, can significantly affect the outcome and scoring potential. Adjust your betting strategy accordingly.

Line movements and public betting: Pay attention to line movements and public betting trends. These can provide valuable insights into how the majority of bettors are leaning and whether there might be value in taking the contrarian approach.

Prop bets and alternative markets: Look beyond the traditional spread and over/under bets. Prop bets, player performance bets, and alternative markets can offer interesting opportunities, especially if you have in-depth knowledge about specific players or matchups.

Manage your bankroll: Set a budget for your wagers and avoid chasing losses. It's important to bet responsibly and not wager more than you can afford to lose. Develop a staking plan and stick to it, adjusting your bet sizes based on your confidence in each pick.

Remember, betting on sports is inherently risky, and there are no guaranteed strategies for success. These tips are meant to provide a framework for making informed decisions, but ultimately, outcomes can be unpredictable. Exercise caution and always gamble responsibly.