NFL Betting Guide: Odds, Trends & Picks For Week 15

NFL Betting Lines, Odds & Picks For Week 15

The NFL season moves into Week 15, and BetQL is your source for NFL best bets, live NFL public bets, live NFL sharp data, NFL line movement and historical betting trends in addition to our NFL articles that cover the sport from top to bottom. Scroll down to see all the best bets and key betting trends for this week's top matchups.

One trend to note is that the BetQL NFL model is on fire, going 37-27 (58%) on all NFL spread picks in the last 30 days for a total return of $704 on $100 bets! BetQL subscribers can see more betting trends and all of our best NFL bets, including player props, with star ratings for every pick.

Take advantage of BetQL's free trial and see all of this week's best NFL bets, plus what the model is projecting for every NBA, NHL, college football and college basketball game! Start your free trial today!

MORE: SPORTSBOOKS’ BEST PROMOS FOR NFL WEEK 15

49ers at Seahawks

ATS Record: 49ers 8-5, Seahawks 6-7

O/U Record: 49ers 6-7, Seahawks 8-5

With a win on Thursday, the 49ers can wrap up the NFC West. They already beat Seattle once this year and another win would give them a three-game lead with three weeks left and the head-to-head tiebreaker. Brock Purdy proved to be a more than adequate replacement in his first career start. The 49ers have now won six in a row, scoring more than 30 points in four of those wins while giving up an average of 10.7 points per game during that stretch. Meanwhile, the Seahawks are 1-3 over their last four games, going 0-4 ATS during that stretch. The only silver lining is the Seahawks have won 10 of their last 11 home games against San Francisco. Also, the Seahawks are 20-8 ATS as home underdogs under Pete Carroll.

Bet NFL risk-free up to $1,000 at BetMGM right now! Take advantage below!

Colts at Vikings

ATS Record: Colts 5-8, Vikings 6-6-1

O/U Record: Colts 4-9, Vikings 8-5

Despite last week’s loss, it’ll take just one more win for the Vikings to clinch the NFC North. Minnesota has gone 4-2 ATS as a home favorite this year. The Vikings also have the benefit of facing an Indy team that’s lost three in a row. The Colts had a bye last week, although they’re still coming off a 54-19 loss to the Cowboys. Plus, the Colts are just 2-5 ATS on the road.

New FanDuel users get a No Sweat First Bet up to $1,000 with the offer below!

Ravens at Browns

ATS Record: Ravens 5-7-1, Browns, 6-7

O/U Record: Ravens 4-9, Browns 7-5-1

After a pair of close wins the last two weeks, the Ravens are neck and neck with Cincinnati atop the AFC North heading down the stretch. Baltimore opened as a road underdog in this game with concerns about the health of QBs Lamar Jackson and Tyler Huntley. However, the Ravens won last week as a road underdog and are 2-0-1 ATS as underdogs in 2022. Meanwhile, the Cleveland offense sputtered last week with the Browns now having lost two of the three games this season in which they’ve been favored at home.

Want $150 in free bets? Sign up for a new DraftKings account, bet $5 and get $150 in free bets! Take advantage below!

Dolphins at Bills

ATS Record: Dolphins 6-7, Bills 6-6-1

O/U Record: Dolphins 6-7, Bills 3-10

Four straight Buffalo wins and two straight losses by everyone else in the division have put the Bills in control of the AFC East. Of course, that can change if the Dolphins win this week and complete a sweep of the Bills, which is something Miami hasn’t done since 2011. Of course, the Dolphins had lost seven in a row against the Bills before beating Buffalo earlier this season. They’ve also lost nine of their last 10 trips to Orchard Park. More recently, the Bills are just 2-5 ATS over their last seven games. At the same time, the Dolphins don’t have an ATS win on the road since beating Baltimore in Week 2.

Bet NFL risk-free up to $1,250 at Caesars right now! Take advantage below!

Eagles at Bears

ATS Record: Eagles 8-5, Bears 4-8-1

O/U Record: Eagles 8-4-1, Bears 9-4

The Eagles appear to be rolling once again, winning their last two games over the Titans and Giants by a combined score of 83-32. They had hit a little bit of a rough patch, but have covered the spread in three straight weeks. The Bears, meanwhile, are heading in the opposite direction. Even with Justin Fields starting to come around, Chicago has lost six in a row and has been officially eliminated from playoff contention. The Bears are also 1-5 ATS during those six losses, although they are 2-2 ATS this year as home underdogs.

Bet NFL risk-free up to $500 at PointsBet right now! Take advantage below!

Falcons at Saints

ATS Record: Falcons 7-6, Saints 5-8

O/U Record: Falcons 6-7, Saints 6-7

Even with four losses in their last five games, the Falcons are just one game behind Tampa in the NFC South with four games left to play. They’re just 1-4 SU but 3-2 ATS as road underdogs this season. They will also feel like they have something to prove after letting their Week 1 lead against the Saints slip away. Of course, Falcons QB Desmond Ridder making his first NFL start adds a wild card to this matchup. Meanwhile, the Saints have lost four of their last five games. New Orleans is also just 3-4 SU at home this year, although the Saints have won and covered in each of the two games in which they’ve been home favorites. They are also 7-2 against the Falcons in the last nine head-to-head games in this rivalry.

Bet NFL risk-free up to $500 at BetRivers right now! Take advantage below!

Lions at Jets

ATS Record: Lions 9-4, Jets 8-5

O/U Record: Lions 9-4, Jets 5-8

With five wins in their last six games, the Lions are very much in the playoff hunt. The Lions are now 5-2 SU in games with a spread of three points or fewer. They’ve also improved to 11-2 ATS during the second half of the season under Dan Campbell. Of course, the Jets are also in a heated playoff race for one of the wild-card spots in the AFC despite losing three of their last four games. While they’ve won their last two home games, they’re just 3-3 SU at home this season and 3-3 SU in games with a spread of four points or fewer.

Steelers at Panthers

ATS Record: Steelers 6-6-1, Panthers 7-6

O/U Record: Steelers 5-8, Panthers 5-8

The Panthers have won back-to-back games, and they’ve done it with Sam Darnold at quarterback, even if Darnold’s numbers are far from impressive. Carolina is also 6-1 ATS over the team’s last seven games. More importantly, the Panthers are just one game behind Tampa in the NFC South, so they are still in the playoff picture. Of course, this will be just the fourth time Carolina will be favored in a game with the Panthers losing all three of the previous games as favorites. As for the Steelers, they suffered a close loss last week, spoiling an opportunity to win a third straight game. But Pittsburgh is also 3-3 ATS as a road underdog, including a pair of SU wins.

Cowboys at Jaguars

ATS Record: Cowboys 8-5, Jaguars 5-8

O/U Record: Cowboys 5-7-1, Jaguars 7-6

Dallas has won four straight games, keeping pressure on the Eagles in the NFC East while also positioning themselves as the top wild-card team. The Cowboys are also 4-1 ATS this season when they’ve been favored by fewer than 10 points. As for the Jags, they beat Tennessee last week to pull within two games of the Titans in the AFC South, keeping Jacksonville alive in the playoff hunt. The Jags are also 3-0 SU as home underdogs this season. In fact, Doug Pederson is 13-4 ATS during his coaching career as a home underdog. However, Pederson is just 4-6 SU in his career against the Cowboys.

Chiefs at Texans

ATS Record: Chiefs 5-8, Texans 4-8-1

O/U Record: Chiefs 6-7, Texans 5-8

For the third time in the last four weeks, the Texans have opened as double-digit underdogs. They’re actually 3-1 ATS as an underdog of at least 10 points this season. Houston also scored 23 points last week, snapping a run of six straight games of scoring fewer than 20 points. But those are the only silver linings during the team’s current eight-game losing streak. As for the Chiefs, one more win can clinch the AFC West title. But they have failed to cover the spread in four of their last six games and are 1-4 ATS this year as a road favorite.

Cardinals at Broncos

ATS Record: Cardinals 6-7, Broncos 5-8

O/U Record: Cardinals 7-6, Broncos 2-11

Leave it to the Broncos to finally get their offensive cranking against the Chiefs. They’ve actually beaten the spread in back-to-back weeks, which is progress for a team that’s already out of the playoff picture. Of course, Russell Wilson (concussion) is questionable for this week, so they could take another step backward if he doesn’t play. Still, Denver is favored this week, though the Broncos are 0-4 ATS when favored this season. Meanwhile, the Cardinals have lost three in a row, including two losses by at least 14 points, and have lost Kyler Murray (ACL) for the rest of the season. But while the Cards are just 4-9 on the season, three of those wins have come as road 'dogs.

Patriots at Raiders

ATS Record: Patriots 7-5-1, Raiders 6-7

O/U Record: Patriots 5-8, Raiders 6-7

The Raiders saw their three-game winning streak end in embarrassing fashion last week, likely spoiling any slim playoff hopes they had. This will be the first time this year that Las Vegas is a home underdog, although the Raiders are 3-1 ATS as underdogs with two SU wins. As for the Patriots, they avoided a three-game losing streak with a win on Monday night. They’ve now won and covered in the four straight games in which they’ve been favored. New England is also 5-2 SU this year against teams that currently have a losing record.

Titans at Chargers

ATS Record: Titans 8-5, Chargers 8-5

O/U Record: Titans 5-8, Chargers 6-7

The Chargers got a massive win over the Dolphins last week to get themselves back in the thick of the playoff race in the AFC. This will also be the last time they play a team with a winning record, so Los Angeles has a favorable schedule down the stretch. Of course, last week’s win over Miami was the first time the Chargers beat a team this year that currently has a winning record. Meanwhile, the Titans have a two-game lead atop the AFC South despite losing three in a row. Despite that lead in the division, Tennessee is in need of a win, especially with the Titans averaging just 16.0 points per game during their three-game losing streak. On the bright side, Tennessee is 3-0 ATS against the AFC West this year and 5-2 ATS on the road.

Bengals at Buccaneers

ATS Record: Bengals 10-3, Buccaneers 3-9-1

O/U Record: Bengals 4-8-1, Buccaneers 3-10

Fans should savor this game because it might be the only matchup between Joe Burrow and Tom Brady that we ever get. The Bengals are heading to Tampa on a five-game winning streak, going 5-0 ATS during that stretch. They’ve also gone 3-2 SU and 3-2 ATS when they’ve been favored on the road this year. As for the Bucs, they are reluctant division leaders. At 6-7, Tampa is just one game ahead of the Panthers and Falcons in the NFC South. The Bucs have also lost three in a row ATS and are coming off a 35-7 loss last week in the first game that they’ve been underdogs this year.

Giants at Commanders

ATS Record: Giants 9-4, Commanders 7-5-1

O/U Record: Giants 5-7-1, Commanders 4-8-1

Two weeks after playing to a 20-20 tie, these teams meet again with the same record and an equal level of desperation, as the loser could easily fall out of a playoff spot. The Giants have the added problem of winning just once in their last six games, and that win came against the lowly Texans. That being said, the G-Men are still 7-2 ATS as an underdog despite getting thrashed by the Eagles last week. Meanwhile, the Commanders had a bye last week following their tie with the Giants, giving them a four-game unbeaten stretch. This week’s game will be just the third time the Commanders have been favored at home; Washington has won and covered in each of the first two.

Rams at Packers

ATS Record: Rams 4-8-1, Packers 5-8

O/U Record: Rams 5-8, Packers 7-6

Baker Mayfield might deserve a league-wide apology after leading the Rams to a comeback win last week to help the reigning champs snap a six-game losing streak. With that win, the Rams are now 6-0 ATS in December over the last two years and 17-8 ATS in December under Sean McVay. However, they are also 1-4 SU and 1-3-1 ATS on the road this season. Meanwhile, the Packers are technically still alive in the playoff race, although they don’t have an easy schedule down the stretch. They are also 2-3 SU and 1-4 ATS when they are favored at Lambeau Field in 2022.

MORE MNF: STAFF PICKS | PLAYER PROPS

BetQL subscribers get more betting trends and all of our best bets, including player props, with star ratings for every pick. Take advantage of BetQL's free trial and see all of this week's best NFL bets, plus what the model is projecting for every NBA, NHL, college football and college basketball game! Start your free trial today!