Biggest Week 10 College Football Spreads

A look at the biggest college football spreads for Week 10

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Week 10 of college football will be fantastic with the No. 1 Georgia Bulldogs taking on No. 2 Tennessee. What about the rest of the country, though?

Here’s a look at the college football odds to see who the largest favorites are this weekend.

1. Ohio State (-38.5) at Northwestern

Ryan Day and the Ohio State Buckeyes (8-0) are expected to have a comfortable blowout victory in their trip to Evanston. Anything less would be shocking.

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2. Oregon (-31.5) at Colorado

Dan Lanning and the Oregon Ducks (7-1) haven’t lost since their opener against the Georgia Bulldogs. They figure to make quick work of the Colorado Buffaloes (1-7), one of the worst teams in the country.

3. Florida International at North Texas (-21.5)

After three straight losing seasons, Seth Littrell’s North Texas Mean Green (5-4) are tied for first in the Conference USA standings. They figure to improve upon their perfect 4-0 conference record in a soft matchup in Week 10.

4. Navy at Cincinnati (-20.5)

It’s not often that the Cincinnati Bearcats are coming off a loss lately under Luke Fickell, but that will be the case in Week 10 after falling short to the UCF Knights a week ago. They are expected to cruise at home over the Navy Midshipmen (3-5).

 
 
 
 
 
 
 
 
 
 
 
 
 
 

T5. Michigan State at Illinois (-16.5)

Can Bret Bielema’s Illinois Fighting Illini (7-1) make it seven straight wins? Their improbable run toward the Big Ten championship game continues as they are three-score favorites at home.

T5. Western Kentucky (-16.5) at Charlotte

The Western Kentucky Hilltoppers (5-4) are heavy favorites on the road but will have to be careful after the Charlotte 49ers pulled off a 56-23 win in their first game under interim head coach Pete Rossomando a week ago.

7. New Mexico at Utah State (-15.5)

The Utah State Aggies are just 3-5 yet are -15.5 favorites over the New Mexico Lobos (2-6), which tells you everything you need to know about the state of Danny Gonzales’s football team.

8. Massachusetts at Connecticut (-14.5)

It looks like Jim Mora is doing something right in Year 1, as his UConn Huskies (4-5) can go from 1-11 a year ago to bowl eligible this season with just two more victories.

T9. Alabama (-13.5) at LSU

One of the games of the weekend has Nick Saban and the Alabama Crimson Tide (7-1) heading to Baton Rouge to welcome Brian Kelly to this heated rivalry.

T9. Minnesota (-13.5) at Nebraska

P.J. Fleck and the Minnesota Golden Gophers (5-3) look to become bowl eligible with a win over the lowly Nebraska Cornhuskers (3-5).

T9. Penn State (-13.5) at Indiana

Will this be a letdown spot for James Franklin’s team? The betting market doesn’t seem to think so in this road matchup.

T9. Liberty at Arkansas (-13.5)

The Liberty Flames pulled off a 41-14 victory in their last game as plus-7 underdogs against the BYU Cougars. Hugh Freeze hopes to rally his team for an even bigger upset in Fayetteville.

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